Normal DNA Methylation Dynamics in DICER1-Deficient Mouse Embryonic Stem Cells

Reduced DNA methylation has been reported in DICER1-deficient mouse ES cells. Reductions seen at pericentric satellite repeats have suggested that siRNAs are required for the proper assembly of heterochromatin. More recent studies have postulated that the reduced methylation is an indirect effect: t...

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Detaylı Bibliyografya
Asıl Yazarlar: Ip, Jonathan, Canham, Paul, Choo, K. H. Andy, Inaba, Yoshimi, Jacobs, Shelley A., Kalitsis, Paul, Mattiske, Deidre M., Ng, Jane, Saffery, Richard, Wong, Nicholas C., Wong, Lee H., Mann, Jeffrey R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435250/
https://ncbi.nlm.nih.gov/pubmed/22969435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002919
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