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Optogenetic control of phosphoinositide metabolism

Phosphoinositides (PIs) are lipid components of cell membranes that regulate a wide variety of cellular functions. Here we exploited the blue light-induced dimerization between two plant proteins, cryptochrome 2 (CRY2) and the transcription factor CIBN, to control plasma membrane PI levels rapidly,...

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Autores principales: Idevall-Hagren, Olof, Dickson, Eamonn J., Hille, Bertil, Toomre, Derek K., De Camilli, Pietro
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435206/
https://ncbi.nlm.nih.gov/pubmed/22847441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211305109
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