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EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection

The fungus Candida albicans is the major cause of oropharyngeal candidiasis (OPC). A key feature of this disease is fungal invasion of oral epithelial cells, a process that can occur by active penetration and fungal-induced endocytosis. Two invasins, Als3 and Ssa1, induce epithelial cell endocytosis...

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Autors principals: Zhu, Weidong, Phan, Quynh T., Boontheung, Pinmanee, Solis, Norma V., Loo, Joseph A., Filler, Scott G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435201/
https://ncbi.nlm.nih.gov/pubmed/22891338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117676109
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