Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors

During oropharyngeal candidiasis (OPC), Candida albicans invades and damages oral epithelial cells, which respond by producing proinflammatory mediators that recruit phagocytes to foci of infection. The ephrin type-A receptor 2 (EphA2) detects β-glucan and plays a central role in stimulating epithel...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Swidergall, Marc, Solis, Norma V., Millet, Nicolas, Huang, Manning Y., Lin, Jianfeng, Phan, Quynh T., Lazarus, Michael D., Wang, Zeping, Yeaman, Michael R., Mitchell, Aaron P., Filler, Scott G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850503/
https://ncbi.nlm.nih.gov/pubmed/33471869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009221
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