Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors

During oropharyngeal candidiasis (OPC), Candida albicans invades and damages oral epithelial cells, which respond by producing proinflammatory mediators that recruit phagocytes to foci of infection. The ephrin type-A receptor 2 (EphA2) detects β-glucan and plays a central role in stimulating epithel...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Swidergall, Marc, Solis, Norma V., Millet, Nicolas, Huang, Manning Y., Lin, Jianfeng, Phan, Quynh T., Lazarus, Michael D., Wang, Zeping, Yeaman, Michael R., Mitchell, Aaron P., Filler, Scott G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850503/
https://ncbi.nlm.nih.gov/pubmed/33471869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009221
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