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Dynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cells

Heregulin (HRG) belongs to the family of EGFs and activates the receptor proteins ErbB3 and ErbB4 in a variety of cell types to regulate cell fate. The interactions between HRG and ErbB3/B4 are important to the pathological mechanisms underlying schizophrenia and some cancers. Here, we observed the...

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Autors principals: Hiroshima, Michio, Saeki, Yuko, Okada-Hatakeyama, Mariko, Sako, Yasushi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435199/
https://ncbi.nlm.nih.gov/pubmed/22891299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200464109
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