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Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder

The role of astrocytes in neurodegenerative processes is increasingly appreciated. Here we investigated the contribution of astrocytes to neurodegeneration in multiple sulfatase deficiency (MSD), a severe lysosomal storage disorder caused by mutations in the sulfatase modifying factor 1 (SUMF1) gene...

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Bibliografische gegevens
Hoofdauteurs: Di Malta, Chiara, Fryer, John D., Settembre, Carmine, Ballabio, Andrea
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435187/
https://ncbi.nlm.nih.gov/pubmed/22826245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209577109
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