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Inhibition of mRNA maturation in trypanosomes causes the formation of novel foci at the nuclear periphery containing cytoplasmic regulators of mRNA fate

Maturation of all cytoplasmic mRNAs in trypanosomes involves trans-splicing of a short exon at the 5′ end. Inhibition of trans-splicing results in an accumulation of partially processed oligocistronic mRNAs. Here, we show that the accumulation of newly synthesised partially processed mRNAs results i...

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Main Authors: Kramer, Susanne, Marnef, Aline, Standart, Nancy, Carrington, Mark
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434824/
https://ncbi.nlm.nih.gov/pubmed/22366449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.099275
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