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Focal adhesion kinase modulates Cdc42 activity downstream of positive and negative axon guidance cues

There is biochemical, imaging and functional evidence that Rho GTPase signaling is a crucial regulator of actin-based structures such as lamellipodia and filopodia. However, although Rho GTPases are believed to serve similar functions in growth cones, the spatiotemporal dynamics of Rho GTPase signal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Myers, Jonathan P., Robles, Estuardo, Ducharme-Smith, Allison, Gomez, Timothy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434813/
https://ncbi.nlm.nih.gov/pubmed/22393238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.100107
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