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Clostridium difficile MazF Toxin Exhibits Selective, Not Global, mRNA Cleavage

Clostridium difficile is an important, emerging nosocomial pathogen. The transition from harmless colonization to disease is typically preceded by antimicrobial therapy, which alters the balance of the intestinal flora, enabling C. difficile to proliferate in the colon. One of the most perplexing as...

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Detalhes bibliográficos
Main Authors: Rothenbacher, Francesca P., Suzuki, Motoo, Hurley, Jennifer M., Montville, Thomas J., Kirn, Thomas J., Ouyang, Ming, Woychik, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434716/
https://ncbi.nlm.nih.gov/pubmed/22544268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00217-12
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