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Glucocorticoid-induction of hypothalamic aromatase via its brain-specific promoter

In the brain, a 36-kb distal promoter (I.f) regulates the Cyp19a1 gene that encodes aromatase, the key enzyme for estrogen biosynthesis. Local estrogen production in the brain regulates critical functions such as gonadotropin secretion and sexual behavior. The mechanisms that control brain aromatase...

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Autors principals: Brooks, DC, Zhao, H, Yilmaz, B, Coon, VJS, Bulun, SE
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434699/
https://ncbi.nlm.nih.gov/pubmed/22705581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.05.012
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