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Glucocorticoid-induction of hypothalamic aromatase via its brain-specific promoter
In the brain, a 36-kb distal promoter (I.f) regulates the Cyp19a1 gene that encodes aromatase, the key enzyme for estrogen biosynthesis. Local estrogen production in the brain regulates critical functions such as gonadotropin secretion and sexual behavior. The mechanisms that control brain aromatase...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434699/ https://ncbi.nlm.nih.gov/pubmed/22705581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.05.012 |
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