Rapid engraftment of human ALL in NOD/SCID mice involves deficient apoptosis signaling

Previously, we found that rapid leukemia engraftment (short time to leukemia, TTL(short)) in the NOD/SCID/huALL (non-obese diabetic/severe combined immuno-deficiency/human acute lymphoblastic leukemia) xenograft model is indicative of early patient relapse. As earlier intact apoptosis sensitivity wa...

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Main Authors: Queudeville, M, Seyfried, F, Eckhoff, S M, Trentin, L, Ulrich, S, Schirmer, M, Debatin, K-M, Meyer, L H
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434672/
https://ncbi.nlm.nih.gov/pubmed/22875001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.107
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