The antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stress

Falcarindiol (FAD) is a natural polyyne with various beneficial biological activities. We show here that FAD preferentially kills colon cancer cells but not normal colon epithelial cells. Furthermore, FAD inhibits tumor growth in a xenograft tumor model and exhibits strong synergistic killing of can...

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Autori principali: Jin, H R, Zhao, J, Zhang, Z, Liao, Y, Wang, C-Z, Huang, W-H, Li, S-P, He, T-C, Yuan, C-S, Du, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434669/
https://ncbi.nlm.nih.gov/pubmed/22914324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.122
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