High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria

The high-mobility group A (HMGA) proteins are a family of non-histone chromatin factors, encoded by the HMGA1 and HMGA2 genes. Several studies demonstrate that HMGA proteins have a critical role in neoplastic transformation, and their overexpression is mainly associated with a highly malignant pheno...

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Bibliografiska uppgifter
Huvudupphovsmän: Esposito, F, Tornincasa, M, Federico, A, Chiappetta, G, Pierantoni, G M, Fusco, A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2012
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434658/
https://ncbi.nlm.nih.gov/pubmed/22932725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.126
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