Unique Biological Activity of Botulinum D/C Mosaic Neurotoxin in Murine Species

Clostridium botulinum types C and D cause animal botulism by the production of serotype-specific or mosaic botulinum neurotoxin (BoNT). The D/C mosaic BoNT (BoNT/DC), which is produced by the isolate from bovine botulism in Japan, exhibits the highest toxicity to mice among all BoNTs. In contrast, r...

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Autores principales: Nakamura, Keiji, Kohda, Tomoko, Shibata, Yuto, Tsukamoto, Kentaro, Arimitsu, Hideyuki, Hayashi, Mitsunori, Mukamoto, Masafumi, Sasakawa, Nobuyuki, Kozaki, Shunji
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434576/
https://ncbi.nlm.nih.gov/pubmed/22665374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00302-12
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