Preliminary X-ray crystallographic study of the receptor-binding domain of the D/C mosaic neurotoxin from Clostridium botulinum

Botulinum toxin (BoNT) from Clostridium botulinum OFD05, isolated from bovine botulism, is a D/C mosaic-type BoNT. BoNTs possess binding, translocation and catalytic domains. The BoNT/OFD05 binding domain exhibits significant sequence identity to BoNT/C, which requires a single ganglioside as a bind...

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Bibliografiske detaljer
Main Authors: Nuemket, Nipawan, Tanaka, Yoshikazu, Tsukamoto, Kentaro, Tsuji, Takao, Nakamura, Keiji, Kozaki, Shunji, Yao, Min, Tanaka, Isao
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2010
Fag:
Crystallization Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864704/
https://ncbi.nlm.nih.gov/pubmed/20445271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110012182
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