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AMPK Regulates Mitotic Spindle Orientation through Phosphorylation of Myosin Regulatory Light Chain

The proper orientation of the mitotic spindle is essential for mitosis; however, how these events unfold at the molecular level is not well understood. AMP-activated protein kinase (AMPK) regulates energy homeostasis in eukaryotes, and AMPK-null Drosophila mutants have spindle defects. We show that...

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Autores principales: Thaiparambil, Jose T., Eggers, Carrie M., Marcus, Adam I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434549/
https://ncbi.nlm.nih.gov/pubmed/22688514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00418-12
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