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In vitro methylation of nascent reovirus mRNA by a virion-associated methyl transferase

Chymotrypsin-derived cores, but not virions, catalyze the transfer of methyl groups from S-adenosyl methionine (SAM) to nascent mRNA synthesized in vitro by the core polymerase. The reaction requires Mg(++), and is dependent on the presence of all 4 ribonucleoside triphosphates (rNTPs). Methylation...

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Publicado en:Nucleic Acids Res
Autores principales: Faust, Manny, Millward, Stewart
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1974
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343453/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4449734/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/1.12.1739
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