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In vitro methylation of nascent reovirus mRNA by a virion-associated methyl transferase

Chymotrypsin-derived cores, but not virions, catalyze the transfer of methyl groups from S-adenosyl methionine (SAM) to nascent mRNA synthesized in vitro by the core polymerase. The reaction requires Mg(++), and is dependent on the presence of all 4 ribonucleoside triphosphates (rNTPs). Methylation...

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Detalhes bibliográficos
Main Authors: Faust, Manny, Millward, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343453/
https://ncbi.nlm.nih.gov/pubmed/4449734
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