Association with Nitric Oxide Synthase on Insulin Secretory Granules Regulates Glucokinase Protein Levels

Glucokinase (GCK) association with insulin-secretory granules is controlled by interaction with nitric oxide synthase (NOS) and is reversed by GCK S-nitrosylation. Nonetheless, the function of GCK sequestration on secretory granules is unknown. Here we report that the S-nitrosylation blocking V367M...

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Detalhes bibliográficos
Main Authors: Markwardt, Michele L., Nkobena, Andongfac, Ding, Shi-Ying, Rizzo, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434526/
https://ncbi.nlm.nih.gov/pubmed/22771492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1183
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