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Naturally Occurring Glucokinase Mutations Are Associated with Defects in Posttranslational S-Nitrosylation
Posttranslational activation of glucokinase (GCK) through S-nitrosylation has been recently observed in the insulin-secreting pancreatic β-cell; however, the function of this molecular mechanism in regulating the physiology of insulin secretion is not well understood. To more fully understand the fu...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Endocrine Society
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802892/ https://ncbi.nlm.nih.gov/pubmed/19934346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0138 |
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