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Naturally Occurring Glucokinase Mutations Are Associated with Defects in Posttranslational S-Nitrosylation

Posttranslational activation of glucokinase (GCK) through S-nitrosylation has been recently observed in the insulin-secreting pancreatic β-cell; however, the function of this molecular mechanism in regulating the physiology of insulin secretion is not well understood. To more fully understand the fu...

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Detalhes bibliográficos
Main Authors: Ding, Shi-Ying, Tribble, Nicholas D., Kraft, Catherine A., Markwardt, Michele, Gloyn, Anna L., Rizzo, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802892/
https://ncbi.nlm.nih.gov/pubmed/19934346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0138
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