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Identification and Proteomic Analysis of Distinct UBE3A/E6AP Protein Complexes
The E6AP ubiquitin ligase catalyzes the high-risk human papillomaviruses' E6-mediated ubiquitylation of p53, contributing to the neoplastic progression of cells infected by these viruses. Defects in the activity and the dosage of E6AP are linked to Angelman syndrome and to autism spectrum disor...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434508/ https://ncbi.nlm.nih.gov/pubmed/22645313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00201-12 |
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