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NEUROG2 Drives Cell Cycle Exit of Neuronal Precursors by Specifically Repressing a Subset of Cyclins Acting at the G(1) and S Phases of the Cell Cycle

Proneural NEUROG2 (neurogenin 2 [Ngn2]) is essential for neuronal commitment, cell cycle withdrawal, and neuronal differentiation. Although NEUROG2's influence on neuronal commitment and differentiation is beginning to be clarified, its role in cell cycle withdrawal remains unknown. We therefor...

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Détails bibliographiques
Auteurs principaux: Lacomme, Marine, Liaubet, Laurence, Pituello, Fabienne, Bel-Vialar, Sophie
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434497/
https://ncbi.nlm.nih.gov/pubmed/22547683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06745-11
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