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Translesion DNA Polymerases and Cancer

DNA repair has been regarded as an important barrier to carcinogenesis. The newly discovered field of translesion synthesis (TLS) has made it apparent that mammalian cells need distinct polymerases to efficiently and accurately bypass DNA lesions. Perturbation of TLS polymerase activity by mutation,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Makridakis, Nick M., Reichardt, Juergen K. V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Research Foundation 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434439/
https://ncbi.nlm.nih.gov/pubmed/22973298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00174
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