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Translesion DNA Polymerases and Cancer
DNA repair has been regarded as an important barrier to carcinogenesis. The newly discovered field of translesion synthesis (TLS) has made it apparent that mammalian cells need distinct polymerases to efficiently and accurately bypass DNA lesions. Perturbation of TLS polymerase activity by mutation,...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Research Foundation
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434439/ https://ncbi.nlm.nih.gov/pubmed/22973298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00174 |
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