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Inhibition of poly(A) polymerase by rifamycin derivatives

The effect of several rifamycin derivatives on poly(A) synthesis in vitro was tested using purified rat liver mitochondrial poly(A) polymerase assayed with an exogenous primer. When used at a concentration of 300 μg/ml, derivatives AF/013, PR/19, AF/AETP, M/88 and AF/ABDP completely inhibited activi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Jacob, Samson T., Rose, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1974
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343433/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10793710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/1.11.1549
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