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Ablation of the calcium-sensing receptor in keratinocytes impairs epidermal differentiation and barrier function
The calcium-sensing receptor (CaR) plays an essential role in mediating Ca(2+)-induced keratinocyte differentiation in vitro. In this study, we generated keratinocyte-specific CaR knockout ((Epid)CaR-/-) mice to investigate the function of the CaR in epidermal development in vivo. (Epid)CaR-/- mice...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434298/ https://ncbi.nlm.nih.gov/pubmed/22622426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.159 |
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