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Impact of signaling microcompartment geometry on GPCR dynamics in live retinal photoreceptors

G protein–coupled receptor (GPCR) cascades rely on membrane protein diffusion for signaling and are generally found in spatially constrained subcellular microcompartments. How the geometry of these microcompartments impacts cascade activities, however, is not understood, primarily because of the ina...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Najafi, Mehdi, Haeri, Mohammad, Knox, Barry E., Schiesser, William E., Calvert, Peter D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434098/
https://ncbi.nlm.nih.gov/pubmed/22891277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210818
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