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Impact of signaling microcompartment geometry on GPCR dynamics in live retinal photoreceptors

G protein–coupled receptor (GPCR) cascades rely on membrane protein diffusion for signaling and are generally found in spatially constrained subcellular microcompartments. How the geometry of these microcompartments impacts cascade activities, however, is not understood, primarily because of the ina...

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Detalhes bibliográficos
Main Authors: Najafi, Mehdi, Haeri, Mohammad, Knox, Barry E., Schiesser, William E., Calvert, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434098/
https://ncbi.nlm.nih.gov/pubmed/22891277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210818
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