Carregant...

Tuning of EAG K(+) channel inactivation: Molecular determinants of amplification by mutations and a small molecule

Ether-à-go-go (EAG) and EAG-related gene (ERG) K(+) channels are close homologues but differ markedly in their gating properties. ERG1 channels are characterized by rapid and extensive C-type inactivation, whereas mammalian EAG1 channels were previously considered noninactivating. Here, we show that...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Garg, Vivek, Sachse, Frank B., Sanguinetti, Michael C.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434097/
https://ncbi.nlm.nih.gov/pubmed/22930803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210826
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!