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Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen-dependent tumorigenesis of MCF-7 breast cancer cells

The AhR was initially identified as a ligand-activated transcription factor mediating effects of chlorinated dioxins and polycyclic aromatic hydrocarbons on cytochrome P450 1 (CYP1) expression. Recently, evidence supporting involvement of the AhR in cell-cycle regulation and tumorigenesis has been p...

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Bibliografiske detaljer
Main Authors: Spink, Barbara C., Bennett, James A., Lostritto, Nicole, Cole, Jacquelyn R., Spink, David C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433635/
https://ncbi.nlm.nih.gov/pubmed/22388733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21889
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