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The tick-derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells
BACKGROUND: Tissue factor (TF) is frequently overexpressed in cancer cells and correlated with more aggressive tumor phenotypes and poor prognosis. In addition to promoting coagulation-dependent metastasis and cancer-associated thrombosis, tumor cell-expressed TF mediates direct cell signaling invol...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433625/ https://ncbi.nlm.nih.gov/pubmed/22823596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2012.04864.x |
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