A Generalized Mathematical Model To Estimate T- and B-Cell Receptor Diversities Using AmpliCot

The efficiency of the adaptive immune system is dependent on the diversity of T- and B-cell receptors, which is created by random rearrangement of receptor gene segments. AmpliCot is an experimental technique that allows the measurement of the diversity of the T- and B-cell repertoire. This procedur...

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Detalhes bibliográficos
Main Authors: Baltcheva, Irina, Veel, Ellen, Volman, Thomas, Koning, Dan, Brouwer, Anja, Le Boudec, Jean-Yves, Tesselaar, Kiki, de Boer, Rob J., Borghans, José A.M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433623/
https://ncbi.nlm.nih.gov/pubmed/23009849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.017
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