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Single-Stranded DNA within Nanopores: Conformational Dynamics and Implications for Sequencing; a Molecular Dynamics Simulation Study

Engineered protein nanopores, such as those based on α-hemolysin from Staphylococcus aureus have shown great promise as components of next-generation DNA sequencing devices. However, before such protein nanopores can be used to their full potential, the conformational dynamics and translocation path...

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Bibliografski detalji
Glavni autori: Guy, Andrew T., Piggot, Thomas J., Khalid, Syma
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433622/
https://ncbi.nlm.nih.gov/pubmed/23009852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.012
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