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Contrasting Factors on the Kinetic Path to Protein Complex Formation Diminish the Effects of Crowding Agents

The crowded environment of cells poses a challenge for rapid protein-protein association. Yet, it has been established that the rates of association are similar in crowded and in dilute solutions. Here we probe the pathway leading to fast association between TEM1 β-lactamase and its inhibitor protei...

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Autors principals: Phillip, Yael, Harel, Michal, Khait, Ruth, Qin, Sanbo, Zhou, Huan-Xiang, Schreiber, Gideon
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433600/
https://ncbi.nlm.nih.gov/pubmed/23009850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.009
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