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Synthesis of 1,N(6)-etheno-2-aza-adenosine (2-aza-ε-adenosine): a new cytotoxic fluorescent nucleoside

1,N(6)-Etheno-2-aza-adenosine was synthesized by treating 1,N(6)-etheno-adenosine with alkali, followed by nitrosation. The mechanism of formation of this novel nucleoside was elucidated using adenosine tritiated at C-8 and C-2, and was found to deformylate exclusively at C-2. This new 2-aza nucleos...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tsou, K.C., Yip, K.F., Miller, E.E., Lo, K.W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1974
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10793738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/1.4.531
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