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Synthesis of 1,N(6)-etheno-2-aza-adenosine (2-aza-ε-adenosine): a new cytotoxic fluorescent nucleoside

1,N(6)-Etheno-2-aza-adenosine was synthesized by treating 1,N(6)-etheno-adenosine with alkali, followed by nitrosation. The mechanism of formation of this novel nucleoside was elucidated using adenosine tritiated at C-8 and C-2, and was found to deformylate exclusively at C-2. This new 2-aza nucleos...

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Bibliographische Detailangaben
Hauptverfasser: Tsou, K.C., Yip, K.F., Miller, E.E., Lo, K.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1974
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC343355/
https://ncbi.nlm.nih.gov/pubmed/10793738
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