Evidence That Sleep Deprivation Downregulates Dopamine D2R in Ventral Striatum in the Human Brain

Dopamine D2 receptors are involved with wakefulness, but their role in the decreased alertness associated with sleep deprivation is unclear. We had shown that sleep deprivation reduced dopamine D2/D3 receptor availability (measured with PET and [(11)C]raclopride in controls) in striatum, but could n...

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Autores principales: Volkow, Nora D., Tomasi, Dardo, Wang, Gene-Jack, Telang, Frank, Fowler, Joanna S., Logan, Jean, Benveniste, Helene, Kim, Ron, Thanos, Panayotis K., Ferré, Sergi
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2012
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433285/
https://ncbi.nlm.nih.gov/pubmed/22573693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0045-12.2012
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