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Purification, crystallization and preliminary X-ray analysis of uracil-DNA glycosylase from Sulfolobus tokodaii strain 7

Uracil-DNA glycosylase (UDG) specifically removes uracil from DNA by catalyzing hydrolysis of the N-glycosidic bond, thereby initiating the base-excision repair pathway. Although a number of UDG structures have been determined, the structure of archaeal UDG remains unknown. In this study, a deletion...

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Autors principals: Kawai, Akito, Higuchi, Shigesada, Tsunoda, Masaru, Nakamura, Kazuo T., Miyamoto, Shuichi
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433208/
https://ncbi.nlm.nih.gov/pubmed/22949205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112030278
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