Regulation of the Hippo-YAP pathway by G-protein coupled receptor signaling

The Hippo pathway is crucial in organ size control and its dysregulation contributes to tumorigenesis. However, upstream signals that regulate the mammalian Hippo pathway have remained elusive. Here we report that the Hippo pathway is regulated by G-protein coupled receptor (GPCR) signaling. Serum-b...

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Hlavní autoři: Yu, Fa-Xing, Zhao, Bin, Panupinthu, Nattapon, Jewell, Jenna L., Lian, Ian, Wang, Lloyd H., Zhao, Jiagang, Yuan, Haixin, Tumaneng, Karen, Li, Hairi, Fu, Xiang-Dong, Mills, Gordon B., Guan, Kun-Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433174/
https://ncbi.nlm.nih.gov/pubmed/22863277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.037
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