Regulation of the Hippo-YAP pathway by G-protein coupled receptor signaling

The Hippo pathway is crucial in organ size control and its dysregulation contributes to tumorigenesis. However, upstream signals that regulate the mammalian Hippo pathway have remained elusive. Here we report that the Hippo pathway is regulated by G-protein coupled receptor (GPCR) signaling. Serum-b...

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Detalhes bibliográficos
Main Authors: Yu, Fa-Xing, Zhao, Bin, Panupinthu, Nattapon, Jewell, Jenna L., Lian, Ian, Wang, Lloyd H., Zhao, Jiagang, Yuan, Haixin, Tumaneng, Karen, Li, Hairi, Fu, Xiang-Dong, Mills, Gordon B., Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433174/
https://ncbi.nlm.nih.gov/pubmed/22863277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.037
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