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Modulating Protein–Protein Interactions with Small Molecules: The Importance of Binding Hotspots
The modulation of protein–protein interactions (PPIs) by small drug-like molecules is a relatively new area of research and has opened up new opportunities in drug discovery. However, the progress made in this area is limited to a handful of known cases of small molecules that target specific diseas...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433052/ https://ncbi.nlm.nih.gov/pubmed/22198293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.026 |
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