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Antibodies to self-antigens predispose to primary lung allograft dysfunction and chronic rejection

BACKGROUND: Primary graft dysfunction (PGD) is a known risk factor for bronchiolitis obliterans syndrome (BOS) following lung transplantation. Here we report that preformed antibodies to self-antigens increase PGD risk and promote BOS. METHODS: Adult lung transplant recipients (n=142) were included...

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Detalhes bibliográficos
Main Authors: Bharat, Ankit, Saini, Deepti, Steward, Nancy, Hachem, Ramsey, Trulock, Elbert P., Patterson, G.A., Meyers, Bryan F., Mohanakumar, T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433047/
https://ncbi.nlm.nih.gov/pubmed/20868794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2010.06.009
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