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Isoflurane Decreases Self-Renewal Capacity of Rat Cultured Neural Stem Cells

BACKGROUND: Isoflurane produces neural and behavioral deficits in in-vitro and in-vivo models. This study tested the hypothesis that neural stem cells are adversely affected by isoflurane such that it inhibits proliferation and kills these cells. METHODS: Sprague Dawley rat embryonic neural stem cel...

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Autori principali: Culley, Deborah J., Boyd, Justin D., Palanisamy, Arvind, Xie, Zhongcong, Kojima, Koji, Vacanti, Charles A., Tanzi, Rudolph E., Crosby, Gregory
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432861/
https://ncbi.nlm.nih.gov/pubmed/21666433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318223b78b
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