NEDDylation regulates E2F-1-dependent transcription

The ubiquitin-like molecule NEDD8 modifies cullin-RING ubiquitin E3 ligases. NEDD8 has been shown to have a few additional substrates, but the extent to which this modification targets non-cullins and the functional significance of such modifications remain unclear. Here, we demonstrate that the cel...

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Autores principales: Loftus, Sarah J, Liu, Geng, Carr, Simon M, Munro, Shonagh, La Thangue, Nicholas B
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
Materias:
Scientific Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432805/
https://ncbi.nlm.nih.gov/pubmed/22836579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.113
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