Dual targeting of mTOR and Aurora-A kinase for the treatment of uterine leiomyosarcoma

PURPOSE: The significance of mTOR activation in uterine leiomyosarcoma (ULMS) and its potential as a therapeutic target were investigated. Furthermore, given that effective therapies likely require combination mTOR blockade with inhibition of other targets, coupled with recent observations suggestin...

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Bibliografiset tiedot
Päätekijät: Savannah, Kari Brewer, Demicco, Elizabeth G., Lusby, Kristelle, Ghadimi, Markus PH., Belousov, Roman, Young, Eric, Zhang, Yiqun, Huang, Kai-Lieh, Lazar, Alexander J., Hunt, Kelly K., Pollock, Raphael E., Creighton, Chad J., Anderson, Matthew L., Lev, Dina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432751/
https://ncbi.nlm.nih.gov/pubmed/22821997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0436
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