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Roles of microRNA-21 and PDCD-4 in the pathogenesis of human uterine leiomyomas

OBJECTIVE: To determine if programmed cell death 4 (PDCD-4) is altered in autologous leiomyoma and myometrial tissues and microRNA-21's (miR-21) role in PDCD-4 expression, apoptosis and translation. DESIGN: Laboratory research. SETTING: Academic medical center. PATIENT(S): Myometrial and leiomy...

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Hlavní autoři: Fitzgerald, J. Browning, Chennathukuzhi, Vargheese, Koohestani, Faezeh, Nowak, Romana A., Christenson, Lane K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432744/
https://ncbi.nlm.nih.gov/pubmed/22728051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2012.05.040
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