Laddar...

New Strategies in Pleural Mesothelioma: BAP1 and NF2 as Novel Targets for Therapeutic Development and Risk Assessment

Malignant pleural mesothelioma (MPM) is a highly lethal cancer with limited therapeutic options. Recent work has identified frequent inactivation of two tumor suppressor genes in MPM-- NF2 (Neurofibromatosis type 2) and BAP1 (BRCA associated protein 1). Additionally, germline mutations in BAP1 have...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Ladanyi, Marc, Zauderer, Marjorie G., Krug, Lee M., Ito, Tatsuo, McMillan, Robert, Bott, Matthew, Giancotti, Filippo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432735/
https://ncbi.nlm.nih.gov/pubmed/22825583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2375
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!