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The Major Isoforms of Bim Contribute to Distinct Biological Activities that Govern the Processes of Autophagy and Apoptosis in Interleukin-7 Dependent Lymphocytes
Bim is a BH3-only member of the Bcl-2 family that enables the death of T-cells. Partial rescue of cytokine-deprived T-cells occurs when Bim and the receptor for the T-cell growth factor, interleukin-7 (IL-7), are deleted, implicating Bim as a possible target of IL-7-mediated signaling. Alternative s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432704/ https://ncbi.nlm.nih.gov/pubmed/22728771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.06.017 |
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