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Disheveled Mediated Planar Cell Polarity Signaling is Required in the Second Heart Field Lineage for Outflow Tract Morphogenesis
Disheveled (Dvl) is a key regulator of both the canonical Wnt and the planar cell polarity (PCP) pathway. Previous genetic studies in mice indicated that outflow tract (OFT) formation requires Dvl1 and 2, but it was unclear which pathway was involved and whether Dvl1/2-mediated signaling was require...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432663/ https://ncbi.nlm.nih.gov/pubmed/22841628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.07.023 |
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