Engineered Mutations Change the Structure and Stability of a Virus-Like Particle

The single coat protein (CP) of bacteriophage Qβ self assembles into T=3 icosahedral virus-like particles (VLPs), of interest for a wide range of applications. These VLPs are very stable, but identification of the specific molecular determinants of this stability is To investigate these determinants...

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Autori principali: Fiedler, Jason D., Higginson, Cody, Hovlid, Marisa L., Kislukhin, Alexander A., Castillejos, Alexandra, Manzenrieder, Florian, Campbell, Melody G., Voss, Neil R., Potter, Clinton S., Carragher, Bridget, Finn, M.G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432585/
https://ncbi.nlm.nih.gov/pubmed/22830650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300590x
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